Table 3.
Nugent Score Over Intervention Period
| Analysis Set (n=36) | Subgroup 1a (n=24) | Subgroup 2b (n=12) | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Mean (SD) | Median | P-value# | Mean (SD) | Median | P-value# | Mean (SD) | Median | P-value# | |
| Day 0 | 3.69 (2.72) | 4.0 | —- | 3.25 (2.94) | 3.0 | —- | 4.58 (2.07) | 5.0 | —- |
| Day 14 | 3.06 (2.66) | 2.0 | 0.177 | 2.58 (2.45) | 2.0 | 0.276 | 4.00 (2.92) | 4.5 | 0.449 |
| Day 28 | 3.56 (2.76) | 3.0 | 0.783 | 2.92 (2.62) | 2.5 | 0.599 | 4.83 (2.69) | 4.5 | 0.775 |
| Day 42 | —- | —- | —- | 3.71 (2.96) | 3.0 | 0.420 | 4.33 (2.46) | 5.0 | 0.709 |
Notes: aIntervention from Day 0 to 28 and follow-up to Day 42; bIntervention from Day 0 to 42; #P-value from paired t-test as compared to baseline.
Abbreviation: SD, standard deviation.