Table 4.
Alpha Diversity Metrics and Percent Relative Abundance of the Most Abundant Phyla and Families Among Vaginal Samples. Mean and SD of Analysis Set at Days 0, 14 and 28
| Day 0 | Day 14 | Day 28 | |||
|---|---|---|---|---|---|
| Mean (SD) | Mean (SD) | P-value# | Mean (SD) | P-value# | |
| Alpha Diversity | |||||
| OTU Richness | 468 (247) | 439 (256) | 0.361 | 392 (201) | 0.141 |
| Shannon Diversity | 1.86 (0.693) | 1.89 (0.737) | 0.509 | 1.84 (0.67) | 0.502 |
| Phylum | |||||
| Firmicutes | 67.0 (34.3) | 67.9 (30.7) | 0.722 | 66.4 (33.2) | 0.721 |
| Bacteroidetes | 13.6 (17.2) | 13.8 (17.2) | 0.594 | 15.9 (19.3) | 0.106 |
| Fusobacteria | 10.3 (16.7) | 6.47 (12) | 0.235 | 10.2 (14.5) | 0.651 |
| Unclassified | 5.22 (7.93) | 4.94 (5.92) | 0.761 | 3.47 (4.35) | 0.259 |
| Family | |||||
| Lactobacillaceae | 58.0 (43.9) | 55.3 (43.2) | 0.980 | 55.1 (44.8) | 0.520 |
| Prevotellaceae | 13.3 (16.8) | 13.5 (16.7) | 0.919 | 15.3 (18.5) | 0.100 |
| Leptotrichiaceae | 10.3 (16.6) | 6.46 (12.0) | 0.271 | 10.0 (14.3) | 0.401 |
| Unclassified | 5.22 (7.93) | 4.94 (5.92) | 0.760 | 3.47 (4.35) | 0.259 |
Note: #P-value from Wilcoxon signed-rank test as compared to baseline.
Abbreviation: SD, standard deviation.