Table 1.
Mean ± SD for behavioral and physiologic parameters measured in the acute and chronic groups treated with control or dirty bedding.
| Acute | Chronic | |||
|---|---|---|---|---|
| Control | Dirty Bedding | Control | Dirty Bedding | |
| Nest Scores | ||||
| D-1 | 3.4 ± 1.1 | 3.5 ± 0.9 | 3.8 ± 0.9 | 4.0 ± 1.2 |
| D1 | 3.7 ± 0.8 | 3.2 ± 0.9 | 3.5 ± 1.0 | 2.6 ± 0.5 |
| D6 | 3.2 ± 0.9 | 3.8 ± 0.8 | ||
| D8 | 3.5 ± 1.4 | 3.3 ± 0.8 | ||
| D13 | 3.8 ± 0.9 | 2.9 ± 0.9 | ||
| D15 | 3.4 ± 1.3 | 3.6 ± 1.0 | ||
| D20 | 3.8 ± 1.4 | 3.5 ± 1.2 | ||
| D22 | 3.5 ± 1.1 | 3.4 ± 1.2 | ||
| D27 | 3.2 ± 0.9 | 2.9 ± 0.7 | ||
| D29 | 3.9 ± 1.1 | 3.6 ± 1.4 | ||
| Light-Dark Box | ||||
| Time Spent in Light Chamber (s) | 125 ± 66 | 174 ± 81 | 100 ± 55 | 142 ± 74 |
| Latency to Enter Dark Chamber (s) | 27 ± 21 | 36 ± 26 | 34 ± 34 | 29 ± 22 |
| Elevated Plus Maze | ||||
| Proportion of Time Spent in the Open Arm | 0.42 ± 0.12 | 0.36 ± 0.10 | 0.41 ± 0.11 | 0.40 ± 0.07 |
| Neutrophil:Lymphocyte Ratio | 0.17 ± 0.03 | 0.17 ± 0.04 | 0.12 ± 0.05 | 0.14 ± 0.04 |
| Weight | ||||
| D0 (g) | 24.45 ± 1.04 | 25.15 ± 0.91 | ||
| D7 (g) | 25.75 ± 0.92 | 25.50 ± 1.08 | ||
| D14 (g) | 27.40 ± 1.07 | 26.55 ± 1.32 | ||
| D21 (g) | 29.35 ± 0.97 | 27.55 ± 1.61* | ||
| D28 (g) | 31.10 ± 1.22 | 28.70 ± 1.57* | ||
| Net Gain (g) | 6.65 ± 1.53 | 3.55 ± 0.90* | ||
*
P < 0.05