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. 2022 Jan 20;15:29–43. doi: 10.2147/PGPM.S338287

Figure 4.

Figure 4

Whole-exome association study with IPA. (A) Manhattan plots showing ACS susceptibility loci discovered in the Chinese ACS WES dataset. Horizontal lines represent the genome-wide threshold (P = 1.2 × 10–5, green). The 4 sites that survived the genome-wide threshold with gene symbols marked in the plot. (B) Q-Q plot. (C) The distribution of IPA in different SNP variation types. 0/0 None, 0/1 heterozygous, 1/1 homozygous variant.