Table 2.
Relationship between COL5A1 expression and immune cell infiltration in different cancers. ∗p < 0.05, ∗∗p < 0.01, and ∗∗∗p < 0.001.
| Cancer type | PRAD p value/Cor |
BRCA p value/Cor |
THCA p value/Cor |
BLCA p value/Cor |
KIRC p value/Cor |
GBM p value/Cor |
KIRP p value/Cor |
|---|---|---|---|---|---|---|---|
| B cells naive | ∗∗∗/0.24 | ∗/0.10 | ∗/0.14 | ∗∗∗/0.23 | ∗∗∗/0.46 | ||
| B cells memory | ∗∗/-0.17 | ∗∗/-0.09 | ∗∗∗/-0.23 | ∗∗/-0.14 | ∗∗∗/-0.31 | ||
| Plasma cells | ∗∗∗/-0.22 | ∗∗∗/0.27 | |||||
| T cells CD8 | ∗∗∗/-0.28 | ∗∗∗/-0.19 | ∗∗∗/-0.23 | ∗∗/-0.17 | |||
| T cells CD4 naive | |||||||
| T cells CD4 memory resting | ∗∗∗/0.32 | ∗∗∗/0.26 | ∗∗/0.16 | ||||
| T cells CD4 memory activated | ∗/-0.10 | ∗∗∗/-0.19 | ∗/0.10 | ∗∗∗/0.16 | ∗∗∗/0.29 | ∗∗∗/0.28 | |
| T cells follicular helper | ∗∗∗/-0.23 | ∗∗∗/-0.20 | ∗/0.10 | ∗∗∗/-0.28 | ∗∗∗/-0.21 | ∗∗∗/-0.28 | ∗∗/0.19 |
| T cells regulatory (Tregs) | ∗∗∗/0.18 | ∗/0.07 | ∗∗∗/0.18 | ∗∗/-0.09 | ∗/0.15 | ||
| T cells gamma delta | ∗∗/-0.09 | ∗∗/-0.13 | |||||
| NK cells resting | ∗∗/-0.16 | ∗∗∗/0.27 | |||||
| NK cells activated | ∗/-0.10 | ∗∗∗/-0.18 | ∗∗/-0.21 | ||||
| Monocytes | ∗∗/0.16 | ∗/0.07 | ∗∗∗/0.18 | ∗/0.13 | ∗∗/-0.13 | ||
| Macrophages M0 | ∗∗∗/-0.21 | ∗/0.07 | ∗∗∗/-0.18 | ∗∗∗/0.22 | ∗∗∗/0.23 | ∗∗∗/0.38 | |
| Macrophages M1 | ∗/-0.11 | ∗∗∗/-0.13 | ∗/0.11 | ∗/-0.19 | ∗∗∗/0.35 | ||
| Macrophages M2 | ∗∗/0.14 | ∗∗∗/-0.25 | ∗∗∗/0.27 | ∗/0.09 | ∗/-0.19 | ∗∗∗/-0.32 | |
| Dendritic cells resting | ∗∗∗/0.23 | ∗∗∗/0.11 | ∗∗∗/0.40 | ∗∗∗/0.24 | |||
| Dendritic cells activated | ∗∗∗/0.23 | ∗∗∗/0.18 | ∗∗∗/-0.23 | ∗∗∗/-0.23 | |||
| Mast cells resting | ∗∗∗/0.23 | ∗∗/0.14 | ∗∗/-0.20 | ∗/-0.13 | |||
| Mast cells activated | ∗/0.15 | ||||||
| Eosinophils | |||||||
| Neutrophils | ∗∗/0.09 | ∗∗/0.17 | ∗∗∗/0.27 |