Table 4.
Subgroup analyses of the association between red cell distribution width to platelet ratio and in-hospital mortality in critically ill patients with acute kidney injury.
| Variables | N | HR (95% CI) | P value | P for interaction |
|---|---|---|---|---|
| Age | 0.075 | |||
| ≤65 years | 10895 | 2.08 (1.93-2.25) | <0.001 | |
| >65 years | 13271 | 1.24 (1.18-1.32) | <0.001 | |
| Gender | 0.375 | |||
| Male | 13897 | 1.46 (1.38-1.55) | <0.001 | |
| Female | 10269 | 1.52 (1.42-1.63) | <0.001 | |
| Ethnicity | 0.803 | |||
| Caucasian | 17338 | 1.49 (1.41-1.157) | <0.001 | |
| Others | 6828 | 1.49 (1.36-1.62) | <0.001 | |
| Congestive heart failure | <0.001 | |||
| No | 16343 | 1.70 (1.60-1.80) | <0.001 | |
| Yes | 7823 | 1.24 (1.16-1.33) | <0.001 | |
| Chronic pulmonary | 0.030 | |||
| No | 18407 | 1.54 (1.46-1.62) | <0.001 | |
| Yes | 5759 | 1.35 (1.24-1.47) | <0.001 | |
| Diabetes | 0.407 | |||
| No | 16579 | 1.52 (1.44-1.60) | <0.001 | |
| Yes | 7587 | 1.45 (1.34-1.57) | <0.001 | |
| Obesity | 0.455 | |||
| No | 22390 | 1.46 (1.40-1.53) | <0.001 | |
| Yes | 1776 | 1.52 (1.23-1.88) | <0.001 | |
| Renal replacement therapy | 0.019 | |||
| No | 22856 | 1.49 (1.42-1.56) | <0.001 | |
| Yes | 1310 | 1.25 (1.08-1.46) | 0.004 | |
| Mechanical ventilation | 0.084 | |||
| No | 10709 | 1.55 (1.45-1.65) | <0.001 | |
| Yes | 13457 | 1.44 (1.35-1.53) | <0.001 | |
| Vasopressor use | 0.001 | |||
| No | 13634 | 1.64 (1.54-1.75) | <0.001 | |
| Yes | 10532 | 1.35 (1.27-1.44) | <0.001 | |
| AKI stage | 0.233 | |||
| Stage 1 | 7010 | 1.57 (1.43-1.72) | <0.001 | |
| Stage 2 | 12015 | 1.44 (1.34-1.54) | <0.001 | |
| Stage 3 | 5141 | 1.36 (1.26-1.48) | <0.001 |
HR: hazard ratio; CI: confidence interval; AKI: acute kidney injury.