TABLE 1.
Differences Between Maternal Parameters of Oxidative Stress With Term Birth or Preterm Birth Outcomes
| Term |
Preterm |
|||||
|---|---|---|---|---|---|---|
| n b | Median (P25, P75) | n b | Median (P25, P75) | p a | ||
| A.U. | ROS (CMH only) | 98 | 8.3 × 105 (5.8 × 105, 1.0 × 106) | 17 | 9.4 × 105 (5.8 × 105, 1.1 × 106) | .696 |
| CMH + SOD | 95 | 8.0 × 105 (6.1 × 105, 1.1 × 106) | 17 | 7.9 × 105 (5.5 × 105, 1.0 × 106) | .375 | |
| CMH + uric acid | 95 | 7.8 × 105 (6.4 × 105, 1.1 × 106) | 17 | 8.1 × 105 (5.9 × 105, 1.2 × 106) | .764 | |
| CMH + DMTU | 93 | 7.7 × 105 (5.6 × 105, 1.2 × 106) | 17 | 7.5 × 105 (5.0 × 105, 9.0 × 105) | .472 | |
| U/ml | CAT | 100 | 5.1 × 104 (2.0 × 104, 8.2 × 104) | 19 | 1.6 × 104 (1.4 × 104, 2.9 × 104) | <.001 |
| SOD | 99 | 8.6 × 104 (5.2 × 104, 1.5 × 105) | 19 | 1.7 × 104 (2.9 × 104, 1.1 × 105) | .025 | |
| nmol/ml | GSH | 98 | 1.7 × 103 (1.4 × 103, 2.1 × 103) | 19 | 1.2 × 103 (1.0 × 103, 1.5 × 103) | <.001 |
| GSSG | 98 | 34.4 (23.5, 47.4) | 19 | 41.4 (31.9, 63.9) | .340 | |
| GSH/GSSG | 98 | 52.0 (35.9, 80.3) | 19 | 23.7 (17.0, 41.0) | .004 | |
Note. A.U. = arbitrary units; ROS = reactive oxygen species; CMH = 1-hydroxy-3-methoxycarbonyl-2,2,5,5-tetramethylpyrrolidine; SOD = superoxide dismutase; DMTU = dimethylthiourea; CAT = catalase; GSH = reduced glutathione; GSSG = oxidized glutathione.
a
Mann–Whitney U with Bonferroni correction (p < .005).
b
Varied from limited or missing specimens.