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. 2021 Dec 22;13(12):e20622. doi: 10.7759/cureus.20622

Table 2. Participants’ behavior regarding the use of medications that contain diphenhydramine hydrochloride (n = 361)*.

*Fifty-three respondents had no previous history of use of medications that contain diphenhydramine hydrochloride; they were excluded from the analysis.

†Variable with multiple response answers.

Characteristics N (%)
On a daily basis, how frequently do you use over-the-counter sleep medications that contain diphenhydramine hydrochloride?
Once per day 231 (31.9%)
Twice per day 9 (2.5%)
Thrice per day 1 (0.30%)
One to two times per week 6 (01.7%)
One to two times per month 14 (03.9%)
Rarely 55 (15.2%)
As needed 45 (12.5%)
On a monthly basis, how frequently do you use over-the-counter sleep medications that contain diphenhydramine hydrochloride?
Once per month 116 (32.1%)
Twice per month 44 (12.2%)
Thrice per month 45 (12.5%)
More than five times per month 8 (2.2%)
A couple of times per week 97 (26.9%)
Rarely 30 (8.3%)
As needed 21 (5.8%)
How many pills do you take at a time
One pill 242 (67%)
Two pills 110 (30.5%)
Three pills 2 (0.60%)
Other 7 (1.9%)
Side effect of sleep medications
Dizziness or imbalance 101 (28%)
Dryness of the mouth, nose, or throat 71 (19.7%)
Anxiety, nervousness, or hyperactivity 64 (17.7%)
Palpitations 60 (16.6%)
Constipation or diarrhea 39 (10.8%)
Abdominal pain 34 (09.4%)
Muscle weakness 31 (08.6%)
Visual disturbances 27 (07.5%)
Nausea or vomiting 25 (06.9%)
Skin irritation 9 (2.5%)
Difficulty or painful urination 7 (1.9%)
Others 3 (0.80%)