Table 3.

Interaction between levels of cognitive activity, social memberships, social participation and other dementia risk factors

Interaction	Level	HR (s.e.)	95% CI	p-Value
Cognitive activities × sex1	High number of cognitive activities × female	0.97 (0.33)	0.49–1.90	0.917
Cognitive activities × education2	High number of cognitive activities × medium	2.04 (0.93)	0.84–4.99	0.117
	High number of cognitive activities × high	0.84 (0.41)	0.33–2.16	0.719
Cognitive activities × wealth3	High number of cognitive activities × medium	0.73 (0.31)	0.31–1.69	0.463
	High number of cognitive activities × high	0.51 (0.22)	0.22–1.20	0.123
Cognitive activities × LIBRAadj4	High number of cognitive activities × high	0.86 (0.30)	0.43–1.71	0.672
Social memberships × sex1	High number of social memberships × female	1.03 (0.26)	0.62–1.70	0.925
Social memberships × education2	High number of social memberships × medium	1.79 (0.57)	0.96–3.32	0.066
	High number of social memberships × high	1.68 (0.56)	0.87–3.23	0.116
Social memberships × wealth3	High number of social memberships × medium	1.09 (0.34)	0.59–2.00	0.793
	High number of social memberships × high	1.06 (0.35)	0.56–2.02	0.853
Social memberships × LIBRAadj4	High number of social memberships × high	0.84 (0.22)	0.51–1.39	0.494
Social participation × sex1	High frequency of social participation × female	1.18 (0.24)	0.86–1.63	0.296
Social participation × education2	High frequency of social participation × medium	1.74 (0.60)	0.88–3.42	0.111
	High frequency of social participation × high	1.64 (0.59)	0.81–3.35	0.171
Social participation × wealth3	High frequency of social participation × medium	1.80 (0.63)	0.91–3.56	0.093
	High frequency of social participation × high	1.45 (0.53)	0.71–2.98	0.307
Social participation × LIBRAadj4	High frequency of social participation × high	1.47 (0.41)	0.86–2.53	0.160

HR, hazard ratio; s.e., standard error; LIBRA_adj, LIfestyle for BRAin health score without the weight for cognitive activity.

¹Adjusted for age, education, wealth and LIBRA_adj scores.

²Adjusted for age, sex, wealth and LIBRA_adj scores.

³Adjusted for age, sex, education and LIBRA_adj scores.

⁴Adjusted for age, sex, education and wealth.