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. 2021 Dec 21;10(2):e257–e268. doi: 10.1016/S2214-109X(21)00497-6

Table 4.

Vaccine delivery outcomes

Needle and syringe (n=917) Disposable syringe jet injector (n=929) Intradermal adapter (n=874)
Intradermal fluid bleb size, mm 7 (5–8) 3 (1–5) 5 (4–7)
Fluid loss onto skin*
Dry 317/880 (36·0%) 288/864 (33·3%) 546/849 (64·3%)
<5 μL 505/880 (57·4%) 263/864 (30·4%) 258/849 (30·4%)
5 to <10 μL 25/880 (2·8%) 76/864 (8·8%) 26/849 (3·1%)
10 to <20 μL 21/880 (2·4%) 65/864 (7·5%) 11/849 (1·3%)
≥20 μL 12/880 (1·4%) 172/864 (19·9%) 8/849 (0·9%)
Time taken to vaccinate
<1 min 300/917 (32·7%) 507/929 (54·6%) 294/874 (33·6%)
1 to <2 min 592/917 (64·6%) 409/929 (44·0%) 553/874 (63·3%)
2 to <3 min 23/917 (2·5%) 11/929 (1·2%) 24/874 (2·7%)
≥3 min 2/917 (0·2%) 2/929 (0·2%) 3/874 (0·3%)
Distress associated with injection
Did not cry 427/917 (46·6%) 771/929 (83·0%) 392/874 (44·9%)
Cried briefly, consoled easily 329/917 (35·9%) 66/929 (7·1%) 351/874 (40·2%)
Crying for a long time 35/917 (3·8%) 12/929 (1·3%) 23/874 (2·6%)
Crying before injection 126/917 (13·7%) 80/929 (8·6%) 108/874 (12·4%)

Data presented as median (IQR) or n/N (%).

*

Fluid loss was not collected on every participant because of the rate of vaccination.