Table 3.
Hospital admission during SARS-CoV-2 infection in unvaccinated population by sex, age, ethnicity, and months of test in 1) <50 years 2) 50 years and above individuals not identified at risk of complication for COVID-19 and 3) individuals identified at risk, January 2021 until April 2021, England.
| Hospital admission in people not identified at risk of complication for COVID-19 | ||||||
|---|---|---|---|---|---|---|
| Variable | Category | Not admitted n(%) | Hospital admission n(%) | Crude OR(95% CI) | Adjusted* OR(95% CI) | LRT p-value |
| under 50 years | ||||||
| Episode n = 3535 | Primary infection | 3428 (97.00) | 106 (3.00) | 1 | 1 | |
| reinfection | 2554 (96.82) | 84 (3.18) | 1.06 (0.80–1.42) | 1.09 (0.81–1.46) | ||
| Age group (Years) n = 6173 | <20 | 474 (97.53) | 12 (2.47) | 1.00 (0.53–1.90) | 1.20 (1.03–1.41) | 0.01 |
| 20 to 29 | 2020 (97.54) | 51 (2.46) | 1 | |||
| 30 to 39 | 1853 (96.81) | 61 (3.19) | 1.30 (0.89–1.90) | |||
| 40 to 49 | 1636 (96.12) | 66 (3.88) | 1.60 (1.10–2.32) | |||
| Sex n = 6144 | Women | 4176 (96.89) | 134 (3.11) | 1 | 1 | 0.70 |
| Men | 1781 (97.11) | 53 (2.89) | 0.93 (0.67–1.28) | 0.94 (0.68–1.30) | ||
| Ethnicity n = 5687 | Asian | 916 (96.12) | 37 (3.88) | 1.28 (0.88–1.86) | 0.69 | |
| Black | 239 (97.55) | 6 (2.45) | 0.80 (0.35–1.83) | |||
| Mixed | 109 (95.61) | 5 (4.39) | 1.46 (0.58–3.63) | |||
| Other | 173 (96.11) | 7 (3.89) | 1.29 (0.59–2.79) | |||
| White | 4067 (96.95) | 128 (3.05) | 1 | |||
| 50 years and older | ||||||
| Episode n = 4806 | Primary infection | 2593 (83.92) | 497 (16.08) | 1 | 1 | |
| reinfection | 1566 (91.26) | 150 (8.74) | 0.50 (0.41–0.61) | 0.51 (0.42–0.63) | ||
| Age group (Years) n = 4808 | 50 to 59 | 1554 (95.99) | 65 (4.01) | 1 | 1 | p<0.0001 |
| 60 to 69 | 682 (86.66) | 105 (13.34) | 3.68 (2.65–5.10) | 3.36 (2.41–4.68) | ||
| 70 to 79 | 432 (68.14) | 202 (31.86) | 11.18 (8.08–15.47) | 9.45 (6.90–12.95) | ||
| 80+ | 1493 (84.45) | 275 (15.55) | 4.40 (3.31–5.85) | 4.33 (3.23–5.79) | ||
| Sex n = 4801 | Women | 2978 (90.00) | 331 (10.00) | 1 | 1 | p<0.0001 |
| Men | 1177 (78.89) | 315 (21.11) | 2.41 (2.03–2.86) | 2.03 (1.70–2.44) | ||
| Ethnicity n = 4553 | Asian | 248 (85.22) | 43 (14.78) | 1.07 (0.77–1.50) | 1.72 (1.19–2.48) | 0.02 |
| Black | 90 (92.78) | 7 (7.22) | 0.48 (0.22–1.05) | 0.66 (0.30–1.47) | ||
| Mixed | 33 (97.06) | 1 (2.94) | 0.19 (0.03–1.38) | 0.36 (0.05–2.66) | ||
| Other | 49 (81.67) | 11 (18.33) | 1.39 (0.72–2.69) | 1.52 (0.75–3.06) | ||
| White | 3505 (86.10) | 566 (13.90) | 1 | |||
| Hospital admission in people identified at risk of complication for COVID-19 | ||||||
| Episode n = 3088 | Primary infection | 1665 (85.47) | 283 (14.53) | 1 | 1 | |
| reinfection | 1024 (89.82) | 116 (10.18) | 0.67 (0.53–0.84) | 0.66 (0.52–0.83) | ||
| Age group (Years) n = 3088 | <20 | 42 (89.36) | 5 (10.64) | 1.36 (0.50–3.70) | 1.17 (1.07–1.28) | p<0.0001 |
| 20 to 29 | 343 (91.96) | 30 (8.04) | 1 | |||
| 30 to 39 | 465 (88.74) | 59 (11.26) | 1.45 (0.91–2.30) | |||
| 40 to 49 | 604 (89.75) | 69 (10.25) | 1.31 (0.83–2.05) | |||
| 50 to 59 | 881 (84.55) | 161 (15.45) | 2.09 (1.38–3.15) | |||
| 60 to 65 | 354 (82.52) | 75 (17.48) | 2.42 (1.54–3.81) | |||
| Sex n = 3076 | Women | 1927 (90.81) | 195 (9.19) | 1 | 1 | p<0.0001 |
| Men | 751 (78.72) | 203 (21.28) | 2.67 (2.15–3.32) | 2.40 (1.92–2.99) | ||
| Ethnicity n = 2970 | Asian | 354 (85.51) | 60 (14.49) | 1.18 (0.87–1.59) | 0.81 | |
| Black | 150 (86.21) | 24 (13.79) | 1.11 (0.71–1.75) | |||
| Mixed | 58 (90.63) | 6 (9.38) | 0.72 (0.31–1.69) | |||
| Other | 52 (72.22) | 20 (27.78) | 2.68 (1.57–4.56) | |||
| White | 1964 (87.44) | 282 (12.56) | 1 | |||
| CEV n = 3088 | No | 2495 (89.46) | 294 (10.54) | 1 | 1 | p<0.0001 |
| Yes | 194 (64.88) | 105 (35.12) | 4.59 (3.50–6.03) | 3.96 (3.01–5.22) | ||
⁎
Odd ratios adjusted for all variable in table provided the p-value for the likelihood ratio test is <0.05.