TABLE 1.
Patient characteristics and surgical procedures
|
Low AAC group N = 53 |
High AAC group N = 150 |
P‐value | |
|---|---|---|---|
| Male/female | 37/16 | 120/30 | .13 |
| Age (y), median (range) | 64 (31–84) | 73 (47–91) | <.01 |
| Child–Pugh classification A/B/C | 50/3/0 | 140/10/0 | 1.00 |
| HCC etiology Nonvirus/HCV/HBV | 9/22/22 | 57/77/16 | <.01 |
| Total bilirubin (mg/dL), median (range) | 0.7 (0.2–2.9) | 0.7 (0.3–2.2) | .87 |
| Smoking Y/N | 24/29 | 96/54 | .02 |
| Hypertension Y/N | 15/38 | 60/90 | .13 |
| Diabetes Y/N | 9/44 | 56/94 | <.01 |
| ALT (IU/L),,median (range) | 31 (10–148) | 32 (10–204) | .97 |
| Albumin (mg/dL),,median (range) | 4.1 (2.5–5.2) | 4.0 (2.3–5.4) | .38 |
| ICGR‐15 (%),,median (range) | 10 (3–66) | 14.3 (3.5–79.1) | <.01 |
| PT (%), median (range) | 87 (13.1–119) | 87 (24–116) | .44 |
| DCP (ng/mL), median (range) | 39 (5–137 910) | 81 (0–223 940) | .14 |
| AFP (mAU/mL), median (range) | 20.5 (0.5–26 170) | 6.7 (0.5–25 230) | .01 |
| Major hepatectomy Y/N | 5/48 | 23/127 | .28 |
| Total cholesterol (mg/dL), median (range) | 170 (110–312) | 166 (101–346) | .70 |
| Triglyceride (mg/dL), median (range) | 88 (42–196) | 96 (28–370) | .09 |
| HbA1c (%), median (range) | 5.3 (4.1–8.9) | 5.7 (4.3–11.2) | <.01 |
| Anatomical hepatectomy Y/N | 20/33 | 37/113 | .07 |
| Operation time (min), median (range) | 288 (161–695) | 299 (116–760) | .42 |
| Blood loss (mL), median (range) | 210 (30–3000) | 350 (20–2750) | .03 |
| Differentiation Poor/moderate/high | 9/36/8 | 11/121/18 | .09 |
| Vascular invasion Y/N | 8/45 | 31/119 | .37 |
| Serosal invasion Y/N | 8/45 | 20/130 | .75 |
| Number of tumor, median (range) | 1 (1–20) | 1 (1–11) | .97 |
| Tumor size (mm), median (range) | 24 (10–130) | 28 (7–335) | .31 |
Abbreviations: ACC, abdominal aortic calcification; AFP, a‐fetoprotein; ALT, alanine aminotransferase; DCP, des‐gamma‐carboxy protein; HCC, hepatocellular carcinoma; HCV, hepatitis virus type C; ICGR‐15, indocyanine green clearance test; PT, prothrombin time.