FIGURE 6.

Upregulation of histone deacetylase (HDAC1), ‐2, and ‐6 in gallbladder carcinoma (GBC) is correlated with a poor prognosis. (A) Expression of HDACs in normal gallbladder and GBC tissues was tested by immunohistochemical staining. Representative IHC staining of HDACs in there GBC tissues and one normal gallbladder. Scale bars: 100 μm. (B) The HDACs expression in 10 normal gallbladder and 100 GBC specimens was quantified with ImageJ software. Data are presented as the mean ± SD (** P < 0.01). (C) Representative micrographs showing low‐level and high‐level expression of HDAC1, HDAC2 and HDAC6 in GBC tissues. Scale bars: 100 μm. (D–F) Survival plots for groups with high and low expression of HDAC1 (D), HDAC2 (E) and HDAC6 (F) in GBC specimens