Table 2.

Classification of patients, response to anti-HCV treatment and MGUS or MM evolution.

Patients	Diagnosis	Monoclonal Ig	Purified	Target of the monoclonal Ig	Antiviral treatment	Decrease in monoclonal Ig	Disease progression	Length, progression-free (months)
P1	MM	IgGλ	Yes	HCV core C1	Yes	Yes	No, stable CR	45
P2	MGUS	IgGκ	Yes	HCV NS3	Yes	Yes	No	46
P3	MGUS	IgGκ	Yes	HCV NS3	Yes	Yes	No	26
P4	MGUS	IgAλ	Yes	HCV NS3	Yes	Yes	No	39
P5	MM Bence-Jones	Light chain κ	Yes	Unknown	Yes	No	Yes, 2 relapses	7
P6	MGUS	IgAλ	Yes	Unknown	Yes	No	No, stable MGUS	17
P7	MGUS	IgGκ	Yes	HCV NS3	No	No	Yes, to SMM	–
P8	MM	IgAλ	Yes	HCV NS3	No	No	Yes, death	–
P9	MM	IgGκ	Yes	HSV-1	No	No	Yes, death	–

MM, multiple myeloma; HCV, hepatitis C virus; CR, complete remission; MGUS, monoclonal gammopathy of undetermined significance; SMM, smoldering multiple myeloma; HSV-1, herpes simplex virus-1.