Table 6.

ROC curve parameters of newly developed metrics to differentiate grade 1 LLT from other grades at 5.33 s

Metric	Sensitivity	Specificity	Area under the curve (CI)	Cut-off value	Youden index	Discriminant power	Accuracy	Kappa index	F-measure
Total area	0.94	0.76	0.89 (0.83–0.96)	117.74	0.70	2.18	0.83	0.72	0.81
Minimum pixel intensity	0.92	0.74	0.88 (0.82–0.95)	67.50	0.65	1.89	0.82	0.70	0.80
Energy	0.87	0.77	0.82 (0.71–0.88)	239.15	0.65	1.77	0.82	0.70	0.80
Relative energy	0.92	0.81	0.91 (0.83–0.96)	0.48	0.73	2.13	0.86	0.76	0.84
SD irregularity	0.89	0.77	0.86 (0.79–0.94)	0.05	0.66	1.83	0.82	0.70	0.79
Mean pixel intensity	0.94	0.79	0.89 (0.83–0.96)	128.62	0.74	2.29	0.86	0.76	0.84
SD of pixel intensity	0.83	0.70	0.78 (0.68–0.88)	28.08	0.53	1.35	0.74	0.57	0.73
Median pixel intensity	0.92	0.81	0.91 (0.84–0.97)	124.50	0.73	2.13	0.86	0.76	0.84
Mode pixel intensity	0.83	0.77	0.87 (0.80–0.94)	133.50	0.61	1.56	0.80	0.66	0.78
Kurtosis	0.89	0.76	0.83 (0.74–0.92)	0.015	0.64	1.77	0.78	0.63	0.76
Skewness	0.92	0.72	0.84 (0.75–0.92)	0.13	0.63	1.84	0.80	0.66	0.78

CI 95% confidence interval, SD standard deviation