Table 1.
Clinical characteristics of the study groups (mean ± SD, range)
| Organ donors (n = 11) | Patients with metastatic liver (n = 13) | pa | |
|---|---|---|---|
| Age (years) | 46.2 ± 12.6 (19–60) | 64.1 ± 8.3 (53–77) | 3 × 10–4 |
| Sex (males/females) | 8/3 | 9/4 | 0.792 |
| Total bilirubin [< 1.23 mg/dL] | 0.70 ± 0.69 (0.1–2.15) | 0.55 ± 0.26 (0.20–1.06) | 0.710 |
| AST [5–40 IU/L] | 33 ± 10 (12–45) | 37 ± 19 (11–65) | 0.756 |
| ALT [5–40 IU/L] | 30 ± 20 (13–89) | 29 ± 18 (10–55) | 0.797 |
| Serum total protein [6.0–8.0 g/dL] | 5.2 ± 1.0 (3.3–6.4) | 6.8 ± 0.7 (5.2–7.5) | 0.002 |
| Serum albumin [3.5–5.5 g/dL] | 2.8 ± 0.7 (1.5–3.6) | 3.8 ± 0.4 (3.4–4.4) | 0.003 |
| INR [0.8–1.2] | 1.23 ± 0.13 (1.0–1.4) | 1.13 ± 0.21 (0.9–1.7) | 0.051 |
| Creatinine [0.6–1.3 mg/dL] | 1.13 ± 0.54 (0.6–1.84) | 0.90 ± 0.23 (0.54–1.34) | 0.477 |
| Administered drugs | Dopamine, dobutamine, epinephrine, lidocaine, sodium nitroprusside, vasopressin, cephalosporines, gentamycin, vancomycin, clindamycin, mannitol | Sevoflurane, propofol, rocuronium, fentanyl, oxycodone, midazolam |
ap value calculated by means of Mann–Whitney U test, except for sex ratio (Chi2 test with Yate’s correction); [ ]—normal range