Table 1.
Time-averaged characteristics of peritoneal dialysis patients stratified by four hemoglobin concentration groups.
| Characteristics | Hemoglobin (g/dL) | ||||
|---|---|---|---|---|---|
| < 10 | 10–10.9 | 11–11.9 | ≥ 12 | p value | |
| N | 2148 | 1445 | 598 | 165 | |
| Age (years) | 50.0 (14.6) | 53.0 (14.4) | 54.3 (14.8) | 53.6 (15.0) | < 0.0001 |
| Age group | |||||
| 20–39 years, n (%) | 537 (25.0) | 258 (17.9) | 103 (17.2) | 30 (18.2) | < 0.0001 |
| 40–64 years, n (%) | 1222 (56.9) | 863 (59.7) | 347 (58.0) | 94 (57.0) | 0.4043 |
| 65–74 years, n (%) | 274 (12.8) | 215 (14.9) | 89 (14.9) | 24 (14.6) | 0.2570 |
| 75 + years, n (%) | 115 (5.4) | 109 (7.5) | 59 (9.9) | 17 (10.3) | 0.0002 |
| Gender | |||||
| Female, n (%) | 1368 (63.7) | 791 (54.7) | 259 (43.2) | 51 (30.9) | < 0.0001 |
| Diabetes, n (%) | 491 (22.9) | 334 (23.1) | 142 (23.8) | 49 (29.7) | 0.2506 |
| Hypertension, n (%) | 1539 (71.7) | 1044 (72.3) | 433 (72.4) | 116 (70.3) | 0.9320 |
| Weekly Kt/V | 2.1 (0.5) | 2.1 (0.5) | 2.1 (0.5) | 1.9 (0.7) | < 0.0001 |
| Weekly CCr (L/week/1.73 m2) | 57.3 (16.0) | 60.8 (17.6) | 63.2 (20.6) | 59.4 (28.0) | < 0.0001 |
| eGFR at the start of dialysis (MDRD) | 4.7 (2.1) | 5.2 (1.9) | 5.7 (2.4) | 6.4 (4.0) | < 0.0001 |
| WBC (× 103/μl) | 5.9 (2.5) | 6.1 (2.4) | 6.1 (2.3) | 6.1 (2.5) | 0.0197 |
| Hemoglobin (g/dL) | 9.1 (0.8) | 10.5 (0.3) | 11.4 (0.3) | 12.6 (0.9) | < 0.0001 |
| Ferritin (ng/dL) | 496.8 (406.7) | 382.7 (316.8) | 372.5 (333.0) | 306.3 (254.5) | < 0.0001 |
| TSAT (%) | 30.5 (11.5) | 30.8 (9.7) | 32.3 (10.4) | 30.4 (10.4) | 0.0061 |
| Serum calcium (mg/dL) | 9.0 (2.0) | 9.0 (1.8) | 8.9 (2.0) | 8.7 (2.5) | 0.1551 |
| Serum phosphate (mg/dL) | 5.3 (1.2) | 5.0 (0.9) | 4.8 (0.9) | 4.7 (1.1) | < 0.0001 |
| Alkaline phosphatase (U/L) | 108.0 (57.3) | 106.3 (57.8) | 107.0 (55.5) | 105.3 (56.8) | 0.8074 |
| Intact-PTH (pg/L) | 307.6 (264.4) | 277.3 (225.6) | 252.7 (235.3) | 237.0 (205.6) | < 0.0001 |
| Uric acid (mg/dL) | 7.1 (1.3) | 6.9 (1.2) | 6.9 (1.4) | 7.1 (1.7) | < 0.0001 |
| Cholesterol (mg/dL) | 199.2 (38.3) | 200.6 (35.8) | 195.1 (37.2) | 191.6 (39.0) | 0.0015 |
| Triglyceride (mg/dL) | 196.4 (122.6) | 172.7 (99.0) | 168.3 (83.0) | 192.1 (103.0) | < 0.0001 |
| nPCR | 0.1 (0.3) | 0.1 (0.3) | 0.1 (0.2) | 0.1 (0.3) | 0.0115 |
| Albumin (g/dL) | 3.8 (1.1) | 3.8 (0.3) | 3.8 (0.4) | 3.9 (0.4) | 0.2841 |
| ESA dose, (U/month) | 17,647.8 (7156.9) | 16,314.5 (6183.9) | 14,498.0 (8317.9) | 11,331.8 (8364.6) | < 0.0001 |
| IV Iron, n (%) | 1088 (50.7) | 704 (48.7) | 236 (39.5) | 53 (32.1) | < 0.0001 |
ESA: erythropoiesis-stimulating agent; eGFR: estimated glomerular filtration rate; IV: intravenous; nPCR: normalized protein catabolic rate; PTH, parathyroid hormone; TSAT: transferrin saturation; WBC: white blood cell counts. All values are expressed as the mean (SD) unless otherwise specified.