Table 3.
Time-averaged characteristics of peritoneal dialysis patients stratified by four TSAT percentage groups.
| Characteristics | TSAT (%) | ||||
|---|---|---|---|---|---|
| < 20 | 20–29 | 30–49 | ≥ 50 | p value | |
| n | 436 | 1892 | 1828 | 200 | |
| Age (years) | 50.8 (13.9) | 52.0 (13.8) | 51.3 (15.6) | 54.5 (16.2) | 0.0117 |
| Age group | |||||
| 20–39 years, n (%) | 95 (21.8) | 359 (19.0) | 436 (23.9) | 38 (19.0) | 0.0031 |
| 40–64 years, n (%) | 267 (61.2) | 1173 (62.0) | 982 (53.7) | 104 (52.0) | < 0.0001 |
| 65–74 years, n (%) | 48 (11.0) | 253 (13.4) | 265 (14.5) | 36 (18.0) | 0.0769 |
| 75 + years, n (%) | 26 (6.0) | 107 (5.7) | 145 (7.9) | 22 (11.0) | 0.0038 |
| Gender | |||||
| Female, n (%) | 266 (61.0) | 1094 (57.8) | 1006 (55.0) | 103 (51.5) | 0.0361 |
| Diabetes, n (%) | 154 (35.3) | 486 (25.7) | 332 (18.2) | 44 (22.0) | < 0.0001 |
| Hypertension, n (%) | 316 (72.5) | 1411 (74.6) | 1311 (71.7) | 94 (47.0) | < 0.0001 |
| Weekly Kt/V | 2.0 (0.7) | 2.1 (0.4) | 2.1 (0.4) | 1.9 (0.7) | < 0.0001 |
| Weekly CCr (L/week/1.73 m2) | 57.9 (22.7) | 59.8 (16.8) | 59.7 (17.0) | 53.8 (23.0) | < 0.0001 |
| eGFR at the start of dialysis (MDRD) | 5.3 (3.7) | 4.9 (2.0) | 5.0 (1.6) | 5.9 (4.1) | < 0.0001 |
| WBC (× 103/μl) | 6.5 (2.7) | 6.2 (2.4) | 5.8 (2.3) | 5.8 (2.7) | < 0.0001 |
| Hemoglobin (g/dL) | 9.7 (1.3) | 10.0 (1.1) | 10.1 (1.1) | 9.7 (1.5) | < 0.0001 |
| Ferritin (ng/dL) | 239.9 (225.5) | 352.0 (266.9) | 501.4 (364.1) | 1031.2 (657.8) | < 0.0001 |
| TSAT (%) | 16.4 (4.7) | 25.5 (2.8) | 36.4 (4.9) | 62.4 (12.5) | < 0.0001 |
| Serum calcium (mg/dL) | 8.9 (2.1) | 9.0 (1.9) | 8.9 (1.9) | 8.6 (2.3) | 0.0133 |
| Serum phosphate (mg/dL) | 5.5 (1.2) | 5.3 (1.0) | 5.0 (1.0) | 4.9 (1.2) | < 0.0001 |
| Alkaline phosphatase (U/L) | 110.7 (63.6) | 108.1 (57.5) | 104.6 (54.7) | 115.1 (61.9) | 0.0199 |
| Intact-PTH (pg/L) | 286.1 (263.6) | 293.7 (252.2) | 284.1 (232.6) | 260.1 (284.5) | 0.2584 |
| Uric acid (mg/dL) | 7.2 (1.6) | 7.1 (1.2) | 6.9 (1.2) | 6.9 (1.3) | < 0.0001 |
| Cholesterol (mg/dL) | 198.1 (49.9) | 202.0 (35.2) | 196.9 (36.1) | 187.6 (35.4) | < 0.0001 |
| Triglyceride (mg/dL) | 197.4 (118.6) | 195.1 (114.4) | 170.8 (101.1) | 180.7 (117.7) | < 0.0001 |
| nPCR | 0.1 (0.3) | 0.1 (0.3) | 0.1 (0.3) | 0.1 (0.3) | 0.6788 |
| Albumin (g/dL) | 3.8 (0.4) | 3.8 (0.3) | 3.8 (1.2) | 3.7 (0.4) | 0.0355 |
| ESA dose, (U/month) | 16,238.0 (10,760.4) | 16,718.5 (6293.3) | 16,390.6 (6790.4) | 16,741.5 (9510.2) | 0.4160 |
| IV Iron, n (%) | 219 (50.2) | 1018 (53.8) | 807 (44.2) | 37 (18.5) | < 0.0001 |
ESA: erythropoiesis-stimulating agent; eGFR: estimated glomerular filtration rate; IV: intravenous; nPCR: normalized protein catabolic rate; PTH, parathyroid hormone; TSAT: transferrin saturation; WBC: white blood cell counts. All values are expressed as the mean (SD) unless otherwise specified.