Table 1.
Descriptive statistics of 683 and 964 participating patients in, respectively, the discovery and replication case–control studies.
| Variable | Description | Discovery (n = 295 + 388) | Replication (n = 476 + 488) | ||||
|---|---|---|---|---|---|---|---|
| OUT | IN | p-value | OUT | IN | p-value | ||
| Sex | Female | 170 (57.63) | 184 (47.42) | 1.69E−02 | 216 (45.38) | 231 (47.34) | 2.39E−26 |
| Male | 124 (42.03) | 200 (51.55) | 177 (37.18) | 256 (52.46) | |||
| UNK | 1 (0.34) | 4 (1.03) | 83 (17.44) | 1 (0.20) | |||
| Age (year) | 1- | 9 (3.06) | 29 (7.47) | 9.53E−04 | 112 (23.53) | 73 (14.96) | 1.15E−06 |
| 20- | 112 (38.1) | 132 (34.02) | 213 (44.75) | 180 (36.89) | |||
| 40- | 139 (47.28) | 151 (38.92) | 105 (22.06) | 148 (30.33) | |||
| 60–100 | 34 (11.56) | 76 (19.59) | 45 (9.45) | 86 (17.62) | |||
| UNK | 1 (0.34) | 1 (0.21) | 1 (0.20) | ||||
| Collection | March | 167 (56.61) | 178 (45.88) | 5.00E−04 | |||
| Month | April | 113 (38.31) | 72 (18.56) | ||||
| May | 12 (4.07) | 24 (6.19) | |||||
| June | 3 (1.02) | 14 (3.61) | 179 (37.61) | 111 (22.75) | 5.00E−06 | ||
| July | 96 (24.74) | 24 (5.04) | 29 (5.94) | ||||
| August | 4 (1.03) | 104 (21.85) | 137 (28.07) | ||||
| September | 21 (4.41) | 16 (3.28) | |||||
| October | 27 (5.67) | 14 (2.87) | |||||
| November | 57 (11.97) | 6 (1.23) | |||||
| December | 4 (0.84) | 10 (2.05) | |||||
| January | 12 (2.52) | 109 (22.34) | |||||
| February | 48 (10.08) | 56 (11.48) | |||||