Table 2.

Association results of selected SNVs (with at least 10 mutations) with hospitalization status (inpatient vs outpatient) in a case–control study of 683 Covid 19 cases: frequencies of wildtypes/mutations among outpatients and inaptients, estimated coefficients, standard errors, p-values, q-values, corresponding residue (if SNV is in the coding region), indicators for urgent SNVs, and corresponding genes.

ID	SNV	Wild/mutant		Unadjusted analysis					Adjusted analysis*					Residue	Genes
		OUT	IN	Coef	SE	Z	p	q	Coef	SE	Z	p	q
1	c241	88/207	101/287	0.19	0.17	1.10	2.72E−01	3.93E−01	0.22	0.17	1.28	1.99E−01	2.93E−01
2	c1059	102/193	207/181	− 0.77	0.16	− 4.85	1.24E−06	8.06E−06	− 0.79	0.16	− 4.94	7.98E−07	4.15E−06	T85I	nsp2
3	c3037	86/209	101/287	0.16	0.17	0.91	3.65E−01	4.74E−01	0.20	0.18	1.12	2.62E−01	3.41E−01	F106F	nsp2
4	c14408	85/210	101/287	0.14	0.17	0.81	4.19E−01	4.95E−01	0.18	0.18	1.00	3.19E−01	3.77E−01
5	t19839	295/0	345/43	>  > 0			1.09E−11		>  > 0					N73N	endoRNase
6	a20268	294/1	343/45	3.65	1.01	3.60	3.16E−04	6.85E−04	3.76	1.02	3.70	2.15E−04	4.67E−04	L216L	endoRNase
7	a23403	88/207	101/287	0.19	0.17	1.10	2.72E−01	3.93E−01	0.22	0.17	1.27	2.03E−01	2.93E−01	D614G	S-spike-protein
8	g25563	98/197	204/184	− 0.80	0.16	− 5.01	5.52E−07	7.18E−06	− 0.83	0.16	− 5.11	3.24E−07	4.15E−06	Q57H	ORF3a
9	c27964	288/7	370/18	0.69	0.45	1.53	1.25E−01	2.32E−01	0.70	0.45	1.55	1.22E−01	2.26E−01	S24L	ORF8
10	c28854	295/0	346/42	>  > 0			2.03E−11		>  > 0					S194L	Nucleocapsid
11	g28881	287/8	334/54	1.76	0.39	4.54	5.66E−06	1.47E−05	1.88	0.39	4.80	1.60E−06	4.15E−06	R203K	Nucleocapsid
12	g28882	287/8	334/54	1.76	0.39	4.54	5.66E−06	1.47E−05	1.88	0.39	4.80	1.60E−06	4.15E−06	R203S**	Nucleocapsid
13	g28883	287/8	334/54	1.76	0.39	4.54	5.66E−06	1.47E−05	1.88	0.39	4.80	1.60E−06	4.15E−06	G204R	Nucleocapsid

*The analysis adjusted age and sex.

**R203S or R203R.