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. 2022 Jan 24;13(1):76. doi: 10.1038/s41419-022-04518-0

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Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — A Image of the mouse lungs in each group, respectively. B The ratio of developing lung metastasis of nude mice was markedly higher in the Nogo-B group than that in the vector-control group. C H&E staining results confirmed the existence of lung xenografts, and the size of lung xenografts of the Nogo-B group were larger in the Nogo-B group. D Immunohistochemical results confirmed the high expression of Nogo-B in the Nogo-B groups.