Table 3.
Coefficients of determination (r2) and slope of parametric [11C]UCB-J DVR, BPND and R1 against corresponding SRTM estimates
| HC | AD | |||
|---|---|---|---|---|
| r2 | Slope | r2 | Slope | |
| Reference Loganb DVR | 0.82 | 0.78 | 0.83 | 0.75 |
| RPMb BPND | 0.92 | 1.00 | 0.97 | 1.02 |
| RPMb R1 | 0.99 | 1.01 | 0.99 | 0.99 |
| SRTM2b BPND | 0.81 | 1.02 | 0.91 | 1.18 |
| SRTM2b R1 | 0.98 | 1.01 | 0.97 | 1.01 |
| MRTMo BPNDb | 0.81 | 0.76 | 0.85 | 0.73 |
| MRTMo b R1 | 0.40 | 0.70 | 0.34 | 0.67 |
| MRTM1b BPND | 0.85 | 0.91 | 0.87 | 0.83 |
| MRTM1b R1 | 0.93 | 1.09 | 0.91 | 1.02 |
| MRTM2b BPND | 0.53 | 0.89 | 0.43 | 1.41 |
| MRTM2b R1 | 0.93 | 1.10 | 0.94 | 1.02 |
| MRT3b BPND | 0.80 | 0.80 | 0.70 | 0.66 |
| MRTM3b R1 | 0.02 | 0.11 | 0.00 | 0.05 |
| MRTM4b BPND | 0.87 | 1.01 | 0.60 | 1.06 |
| MRTM4b R1 | 0.05 | 0.08 | 0.00 | − 0.06 |
BPND: binding potential; MRTM: multilinear reference tissue model; NLR: non-linear regression; RPM: receptor parametric mapping; SRTM2: simplified reference tissue model 2
aPlasma input implementations
bReference region implementations