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. 2022 Jan 11;11:806465. doi: 10.3389/fcimb.2021.806465

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Copyright © 2022 Wu, Fan, Han, Guo and Liu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Sequence analysis of Cdc4 proteins. (A) Schematic illustration of Cdc4 proteins in C. neoformans (CnCdc4), S. cerevisiae (ScCdc4), C. albicans (CaCdc4), and A. fumigatus (AfCdc4). F-box, F-box domain; WD, WD40 domains. (B) C. neoformans Cdc4 protein shows high identity and similarity to the Cdc4 proteins of S. cerevisiae, C. albicans, and A. fumigatus. (C) Comparison of the region spanning F-box and WD40 domains in Cdc4 protein sequences of C. neoformans (CnCdc4), S. cerevisiae (ScCdc4), C. albicans (CaCdc4), and A. fumigatus (AfCdc4). The F-box domain and each WD40 domain were labeled by blue and red round rectangular box, respectively.