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. 2022 Jan 11;8:813984. doi: 10.3389/fcvm.2021.813984

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Copyright © 2022 Mauersberger, Hinterdobler, Schunkert, Kessler and Sager.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Pharmacological targets in atherosclerotic leukocyte recruitment. Simplified overview of approved (black) or potential (gray) targets in the process of leukocyte recruitment into atherosclerotic plaques. Substances with an incompletely clarified mechanism of action are marked with (?). CXCL2, C-X-C motif chemokine ligand 2; ICAM-1, intracellular adhesion molecule 1; ICAM-2, intracellular adhesion molecule 2; NO, nitric oxide; (ox)LDL, (oxidized) lipoprotein; PCSK9, proprotein convertase subtilisin/kexin type 9; VCAM-1, vascular adhesion molecule 1.