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. 2022 Jan 11;12:706478. doi: 10.3389/fneur.2021.706478

Table 3.

Clinical features and outcomes of COVID-19 patients with or without a history of CVD.

Clinical features and outcomes History of CVD n = 109 No history of CVD n = 2,445 P-Value
Time from symptoms to admission, mean ± SD 23.23 ± 14.59 24.07 ± 12.97 0.501
Severity on admission (proportion) <0.001*
Mild cases 1 (0.9) 27 (1.1)
Moderate cases 55 (50.5) 1,731 (70.8)
Severe cases 49 (45.0) 660 (27.0)
Critical cases 4 (3.7) 27 (1.1)
Drug treatment (proportion)
Antibiotics 54 (49.5) 799 (32.7) <0.001
Antivirals 48 (44.0) 1,191 (48.8) 0.333
Immune support 53 (48.6) 801 (32.8) 0.001
Glucocorticoids 26 (23.9) 345 (14.1) 0.005
Mechanical ventilation (proportion) 9 (8.3) 36 (1.5) <0.001
Non-Invasive 7 (6.4) 32 (1.3) <0.001
Invasive 5 (4.6) 12 (0.5) <0.001
ECMO 0 2 (0.1) 1.000
ICU care (proportion) 4 (3.7) 17 (0.7) 0.005
Shock (proportion) 9 (8.3) 47 (1.9) <0.001
Length of hospital day, mean±SD 14.9 (9.9) 14.7 (8.7) 0.818
Clinical outcomes (proportion)
Discharged 102 (93.6) 2,407 (98.4) 0.001
Died 7 (6.4) 38 (1.6) 0.001
Severe events (proportion) 14 (12.8%) 63 (2.6%) <0.001

Data are described as mean ± SD or proportion (%); χ2 test, Fisher exact test, T-test was used to calculate P-values when appropriate.