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. 2022 Jan 11;11:715077. doi: 10.3389/fonc.2021.715077

Figure 4.

Figure 4

Immune cell populations in cervical cancer tissue. Each dot represents one sample. Y-axis indicates the immune cell score (ratio of given cell type relative to CD45+ immune cells). *P < 0.05, **P < 0.01. (A) Total CD45+ lymphocyte score. HC show significantly lower CD45+ cells compared to any cervical cancer group. (B) CD8+ T cells vs. CD45: significant differences between HC vs. each cervical cancer group and CCLR vs. CCDR. (C) CD80+CD86+ Macrophages vs. CD45: significant differences between HC vs. each cervical cancer group and CCLR vs. CCDR (D) CD163+MRC1+ Macrophages vs. CD45: significant differences between HC vs. each cervical cancer group and CCLR vs. CCDR. (E) Tregs vs. CD45: significant differences between HC vs. CCLR, HC vs. CCNR, CCNR vs. CCDR, and CCLR vs. CCDR. Tregs, Regulatory T cells; HC, Healthy controls; CCLR, Cervical cancer local recurrence; CCDR, Cervical cancer distant recurrence; CCNR, Cervical cancer no recurrence.