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A 50-year-old female with systemic lupus erythematosus was diagnosed as having necrotizing fasciitis. (A) The left thigh was red and swollen. (B) The necrosis area extended to the knee. (C) Debridement revealed the necrotic fascia. (D) & (E) Negative pressure wound therapy was applied through three incisions for five weeks. (F) The patient recovered well and was soon discharged.
