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. 2022 Jan 11;11:774558. doi: 10.3389/fonc.2021.774558

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Copyright © 2022 Xing, Yin, Yao and Xing

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Evaluation of the three prognosis models constructed based on FR-DEGs, IR-DEGs, and FI-DEGs. (A–C), ROC plot analysis for FR-DEG model (A), IR-DEG model (B), and FI-DEG model (C). (D–F) The expression profile of the candidate prognosis biomarkers in different models. (D) FR-DEG model. (E) IR-DEG model. (F) FI-DEG models. (G–I) Correlation analysis of the CIFI value of the model with the candidate prognosis biomarkers. (G) FR-DEG model. (H) IR-DEG model. (I) FI-DEG models. *p < 0.05, **p < 0.01, ***p < 0.001. DEGs, differentially expressed genes; FR-DEGs, ferroptosis-related DEGs; IR-DEGs, immune-related DEGs; FI-DEGs, ferroptosis- and immune-related DEGs; ROC, receiver operating characteristic; CIFI, comprehensive index of ferroptosis and immune status.