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. 2022 Jan 11;11:774558. doi: 10.3389/fonc.2021.774558

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Copyright © 2022 Xing, Yin, Yao and Xing

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Independent prognostic factors of overall survival. (A–C) Univariate Cox regression of prognostic factors in three different models. (A) FR-DEG model. (B) IR-DEG model. (C) FI-DEG models. (D–F) Multivariate Cox regression of prognostic factors in three different models. (D) FR-DEG model. (E) IR-DEG model. (F) FI-DEG models. (G–J) ROC curve plot of CESC patients with different clinical features. (G) Age. (H) Pathological T. (I) Pathological N. (J) Pathological M. DEGs, differentially expressed genes; FR-DEGs, ferroptosis-related DEGs; IR-DEGs, immune-related DEGs; FI-DEGs, ferroptosis- and immune-related DEGs; ROC, receiver operating characteristic; CESC, cervical squamous cell carcinoma and endocervical adenocarcinoma.