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Anti-COVID-19 genome editing was performed using the Crisper/Cas system and PAC-MAC function. (A) A mutation in the target gene is caused by the CRISPR/CAS9 system, which is supported by the NHEJ repair mechanism and causes a change in the gene. The gene expression is reduced or stopped depending on the target. (B) Cas13d can inhibit viral activity and replication. Cas13d targets and cleaves 100% of the positive sense RNA produced by viruses.
