TABLE 3.

Heterogeneity test and horizontal pleiotropy test.

Exposure	Outcome	Heterogeneity test (IVW)			Heterogeneity test (MR-Egger)			Horizontal pleiotropy test (MR-Egger)
		Q	I2	p-value	Q	I2	p-value	Intercept	SE	p-value
AD	HF	16.87	35%	0.112	16.86	35%	0.077	0.0006	0.0061	0.921
HF	AD	5.019	-0.6	0.755	4.192	-0.9	0.757	0.0167	0.0183	0.393

AD, Alzheimer’s disease; HF, heart failure; IVW, inverse variance weighted; SE, standard error.