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. 2022 Jan 11;12:796704. doi: 10.3389/fneur.2021.796704

Figure 7.

Figure 7

Effects of microglia on endothelial cells in SCI. Proinflammatory cytokines induce oxidative damage to endothelial cells, ECM degradation, and increased permeability of the BBB by proinflammatory molecules, while anti-inflammatory secretion promotes angiogenesis. Green arrow, downregulation.