Figure 8.

Nano‐OM targeted lung macrophages in ALI mice after intratracheal instillation. a) Gating strategy for the flow cytometry analysis to identify monocytes (Mo), dendritic cells (DCs), macrophages (Mϕ), and neutrophils (PMN) in the BALF. b) Distribution of DiD labeled liposomes (DiD‐Liposome) in various phagocytic immune cells; DiD‐Liposome treatment group is shown in red, and the untreated control group is shown in gray. Quantitative analysis of the amount of DiD‐Liposome internalized in various immune cells in c) the BALF and d) the lung; the uptake of DiD‐Liposome in each type of cells is quantified as the MFI of DiD. DiD‐Liposome: 12.6 mg kg⁻¹ phospholipids, N = 4.