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. 2021 Nov 26;9(3):2102435. doi: 10.1002/advs.202102435

Table 1.

Pathways induced by different ligands from the MSM analysis

Ligand Pathways Percentage of total coarse flux [%]
apo S0A→S1A→S4A 58.0
S0A→S1A→S3A→S4A 34.6
S0A→S4A 5.6
S0A→S1A→S3A→S2A→S4A 1.8
DEX S0B→S3B→S4B 96.0
S0B→S1B→S3B→S4B 3.6
S0B→S4B 0.2
S0B→S1B→S3B→S2B→S4B 0.2
AZD9567 S0C→S1C→S3C→S4C 81.7
S0C→S1C→S2C→S4C 9.4
S0C→S3C→S4C 6.6
S0C→S1C→S4C 1.8
S0C→S3C→S2C→S4C 0.5
RU486 S0D→S2D→S3D→S4D 55.3
S0D→S2D→S4D 23.9
S0D→S1D→S2D→S4D 17.5
S0D→S3D→S4D 3.4