Table 1.
Ligand | Pathways | Percentage of total coarse flux [%] |
---|---|---|
apo | S0A→S1A→S4A | 58.0 |
S0A→S1A→S3A→S4A | 34.6 | |
S0A→S4A | 5.6 | |
S0A→S1A→S3A→S2A→S4A | 1.8 | |
DEX | S0B→S3B→S4B | 96.0 |
S0B→S1B→S3B→S4B | 3.6 | |
S0B→S4B | 0.2 | |
S0B→S1B→S3B→S2B→S4B | 0.2 | |
AZD9567 | S0C→S1C→S3C→S4C | 81.7 |
S0C→S1C→S2C→S4C | 9.4 | |
S0C→S3C→S4C | 6.6 | |
S0C→S1C→S4C | 1.8 | |
S0C→S3C→S2C→S4C | 0.5 | |
RU486 | S0D→S2D→S3D→S4D | 55.3 |
S0D→S2D→S4D | 23.9 | |
S0D→S1D→S2D→S4D | 17.5 | |
S0D→S3D→S4D | 3.4 |