Table 3. Hematology profile and blood biochemistry at pre and 14 days post-treatment in Delman horses with colic.
| Parameters | Ref 22 | Normal ( n = 19) | Colic ( n = 96) | |
|---|---|---|---|---|
| Pre-treatment | 14 d post-treatment | |||
| TRBCs (× 10 6) | 6.5-12.5 | 10.7 ± 0.08 a,*** | 9.6 ± 0.23 b | 10.7 ± 0.12 a,*** |
| HB (mg dL −1) | 11-19 | 13.4 ± 0.08 a,*** | 14.4 ± 0.24 c | 13.6 ± 0.06 b,*** |
| PCV (%) | 32.0-37.4 | 31.1 ± 0.59 b,*** | 52.7 ± 0.58 c | 27.8 ± 0.45 a,*** |
| MCV (fl) | 36-52 | 39.2 ± 0.08 a,*** | 43.7 ± 0.59 b | 39.1 ± 0.13 a,*** |
| MCH (pg) | 12.3-19.7 | 15.2 ± 0.14 a,*** | 18.4 ± 0.09 c | 15.6 ± 0.19 b,*** |
| MCHC (g dL −1) | 34-39 | 335.5 ± 0.91 ab | 334.9 ± 0.63 b | 336.3 ± 0.12 a,** |
| Eosinophil (× 10 3 μL −1) | 0.0-0.9 | 0.8 ± 0.08 a,* | 0.9 ± 0.04 b | 0.8 ± 0.02 ab |
| Neutrophil (× 10 3 μL −1) | 2.7-6.7 | 6.4 ± 0.30 a,*** | 8.9 ± 0.26 c | 7.1 ± 0.08 b,*** |
| Basophil (× 10 3 μL −1) | 0.0-0.2 | 0.1 ± 0.01 a,*** | 0.3 ± 0.02 b | 0.1 ± 0.01 a,*** |
| Monocyte (× 10 3 μL −1) | 0.0-0.8 | 0.7 ± 0.06 ab | 0.7 ± 0.07 b | 0.6 ± 0.01 a,** |
| Lymphocyte (× 10 3 μL −1) | 1.5-5.5 | 5.3 ± 0.18 a,*** | 3.4 ± 0.09 b | 5.2 ± 0.07 a,*** |
| Plt (×1) | 100-600 | 568.4 ± 5.05 b,*** | 256.9 ± 1.21 c | 590.6 ± 3.94 a,*** |
| MPV (fl) | 9.0-10.2 | 8.9 ± 0.11 a,*** | 13.3 ± 0.81 b | 8.4 ± 0.10 a,*** |
| PDW (%) | 14.8-18.4 | 15.7 ± 0.34 b,*** | 19.5 ± 1.19 c | 14.4 ± 0.12 a,*** |
| CT (min) | 2.9-3.9 | 3.2 ± 0.05 a,*** | 5.4 ± 0.08 b | 3.2 ± 0.04 a,*** |
| Prt (sec) | 9.5-12.1 | 10.4 ± 0.29 a,*** | 24.9 ± 0.42 c | 11.1 ± 0.46 b,*** |
| Appt (sec) | 45.7-55.1 | 51.0 ± 0.59 b,*** | 68.1 ± 0.73 c | 48.8 ± 0.34 a,*** |
| Fibrinogen (mg 100 mL −1) | 100-400 | 364.6 ± 5.31 b,*** | 254.8 ± 10.43 c | 382.6 ± 0.87 a,*** |
| Total Protein (gm 100 mL −1) | n/a | 6.1 ± 0.04 a,*** | 7.3 ± 0.17 b | 6.2 ± 0.05 a,*** |
| Albumin (gm 100 mL −1) | n/a | 2.9 ± 0.05 b,*** | 3.8 ± 0.04 c | 2.7 ± 0.04 a,*** |
| Globulin (gm 100 mL −1) | n/a | 3.3 ± 0.05 b,** | 3.5 ± 0.05 c | 2.9 ± 0.09 a,*** |
| Calcium (gm 100 mL −1) | n/a | 11.4 ± 0.12 a,*** | 7.8 ± 0.12 c | 8.7 ± 0.05 b,*** |
Values are expressed in mean ± SD. One-way ANOVA was carried out followed by post hoc Tukey multiple comparisons test. Values are represented statistically when a,b,c, in comparison with normal group; *p < 0.05, **p < 0.01, ***p < 0.001, in comparison with pre-treatment group.
TRBCs = total erythrocyte count; HB = hemoglobin; PCV = packed cell volume; MCV = mean corpuscular volume; MCH = mean corpuscular haemoglobin; MCHC = mean cell hemoglobin concentration; Plt = platelets count; MPV = mean platelets volume; PDW = platelets distribution width; CT = clotting time; Prt = prothrombine time; Appt = activated partial thromboplastine time; n/a = not applicable (reference range not established).