Table 2. . Laboratory parameters of the two patients.
| Laboratory parameters | Reference range | Case 1 | Case 2 |
|---|---|---|---|
| Hemoglobin | Female: 11–15 g/dl; male: 13–17 g/dl | 11.2 | 11.1 |
| Red blood cell count | 3.8–4.8 (106/μl) | 3.65 | 3.25 |
| White blood cell count | 4–11 (103/μl) | 11.88 | 16.38 |
| Neutrophils | 40–80 (%) | 82.5 | ND |
| Lymphocytes | 20–40 (%) | 9.9 | ND |
| Monocytes | 2–10 (%) | 7 | ND |
| Eosinophils | 1–6 (%) | 0.2 | ND |
| Basophils | 1–2 (%) | 0.4 | ND |
| Platelet count | 150–400 (103/μl) | 262 | 277 |
| Total bilirubin | 0.3–1.2 mg/dl | 0.4 | 0.7 |
| ALT | 5–45 u/l | 24 | 95 |
| AST | 5-40 u/l | 34 | 51 |
| ALP | 80–240 u/l | 65 | 587 |
| Urea | <50 mg/dl | 19 | 53 |
| Creatinine | 0.5–1.1 mg/dl | 0.6 | 0.6 |
| Sodium | 132–146 mmol/l | 138 | 137 |
| Potassium | 3.5–5.5 mmol/l | 4 | 5.2 |
| Total protein | 5.7–8.2 g/dl | 6 | 5 |
| Albumin | 3.2–4.8 g/dl | 3 | 2.8 |
| Globulin | 2.5–3.4 g/dl | 2.9 | 2.2 |
| LDH | 140-280 u/l | 304 | ND |
| IL-6 | 5-15 pg/ml | 27.26 | ND |
| Serum ferritin | 10–291 ng/ml | 220.5 | ND |
| Co-infections | |||
| Scrub typhus IgM ELISA (OD) | ≥0.89 | 1.2 | 1.1 |
| Scrub typhus IgM IFA | ≥64 | + | – |
| Nested PCR (56 kDa) | 483 bp | – | – |
| Serology for Rickettsia spp., Leptospira spp., Mycoplasma pneumoniae, Chlamydia pneumoniae and Legionella pneumophila | Refer to Table 3 | – | – |
| Molecular tests for Rickettsia spp., Leptospira spp., M. pneumoniae and L. pneumophila | Refer to Table 3 | – | – |
ALT: Alanine transaminase; ALP: Alkaline phosphatase; AST: Aspartate transaminase; bp: Basepair; ELISA: Enzyme-linked immunosorbent assay; ESR: Erythrocyte sedimentation rate; IFA: Indirect immunofluorescence assay; kDa: Kilodalton; LDH: Lactate dehydrogenase; ND: Not done; OD: Optical density.