Table 3.
Hsa-mir-3940-3p cell signaling pathway (Reactome 2020 database)
| Pathway name | Entities P value | FDR | Genes |
|---|---|---|---|
| Interleukin-4 and interleukin-13 signaling | <0.0001 | <0.0001 | POU2F1;BIRC5;FAN1 |
| Signaling by interleukins | 0.0001 | 0.005 | POU2F1;BIRC5;FAN1 |
| Cytokine signaling in immune system | 0.0003 | 0.010 | POU2F1;LTA;BIRC5;FAN1 |
| TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain | 0.0006 | 0.015 | BIRC5 |
| Immune system | 0.0008 | 0.016 | POU2F1;CYB5R3;ORMDL3;LTA;BIRC5;ANKRD52;FAN1 |
| Manipulation of host energy metabolism | 0.003 | 0.061 | ENO1 |
| TP53 regulates transcription of cell death genes | 0.005 | 0.071 | BIRC5 |
| TYSND1 cleaves peroxisomal proteins | 0.010 | 0.123 | ANKRD52 |
| TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway | 0.021 | 0.133 | LTA |
| Neutrophil degranulation | 0.022 | 0.133 | CYB5R3;ORMDL3;ANKRD52 |
| Mitotic prometaphase | 0.029 | 0.133 | BIRC5;CEP63 |
| Vitamin C (ascorbate) metabolism | 0.033 | 0.133 | CYB5R3 |
| RNA polymerase III transcription initiation from type 3 promoter | 0.035 | 0.133 | POU2F1 |
| TNFs bind their physiological receptors | 0.038 | 0.133 | LTA |
| RNA polymerase III transcription initiation | 0.045 | 0.133 | POU2F1 |
| Beta-oxidation of very long chain fatty acids | 0.047 | 0.133 | ANKRD52 |
| Synthesis of IP3 and IP4 in the cytosol | 0.049 | 0.133 | POU2F1 |
Abbreviation: FDR, false discovery rate