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. 2021 Dec 30;11(1):26–38. doi: 10.1021/acssynbio.1c00547

Table 1. Comparison of Methods Applied in Skin Bioprinting4750.

method printing process accuracy pros cons ref.
Extrusion bioprinting line by line medium-low low cost, simplicity, printability of high cell density and highly viscous bioinks clogging nozzles, mechanical stresses generated while bioink deposition (34,5153)
Inkjet-based biopritning drop by drop medium low cost, high cell viability, high resolution, high throughput, noncontact printing limited bioink, low strength, nozzle clogging, risk of exposing cells to mechanical and thermal stress, possibility of cell agglomeration and sedimentation (28,41,54,55)
Laser-assisted bioprinting drop by drop high high cell viability, noncontact, nozzle-free, high precision and resolution low scalability, low flow rate caused by fast gelation, time-consuming (28,56,57)