Table 3.
SARS-CoV-2: Variants of concern and interest (classified according to WHO)
| Sl. No. | WHO Label | Pango lineages | Spike Protein Substitutions: | Earliest documented samples |
|---|---|---|---|---|
| Variants of concern | ||||
| 1 | Alpha | B.1.1.7 | 69del, 70del, 144del, E484K, S494P, N501Y, A570D, D614G, P681H, T716I, S982A, D1118H K1191N | United Kingdom, Sep-2020 |
| 2 | Beta | B.1.351, B.1.351.2, B.1.351.3 | D80A, D215G, 241del, 242del, 243del, K417N, E484K, N501Y, D614G, A701V | South Africa, May 2020, |
| 3 | Gamma | P.1 P.1.1 P.1.2 P.1.4 P.1.6 P.1.7 | L18F, T20N, P26S, D138Y, R190S, K417T, E484K, N501Y, D614G, H655Y, T1027I | Brazil, Nov 2020 |
| 4 | Delta | B.1.617.2 AY.1 AY.2 AY.3 AY.3.1 |
T19R, V70F, T95I, G142D, E156-, F157-, R158G, A222V, W258L, K417N, L452R, T478K, D614G, P681R, D950N | India, Oct2020 |
| Variants of interest | ||||
| 5 | Eta | B.1.525 | A67V, 69del, 70del, 144del, E484K, D614G, Q677H, F888 | Multiple countries, Dec-2020 |
| 6 | Iota | B.1.526 | L5F, D80G, T95I, Y144-, F157S, D253G, L452R, S477N, E484K, D614G, A701V, T859N, D950H, Q957R | United States of America Nov 2020 |
| 7 | Kappa | B.1.617.1 | T95I, G142D, E154K, L452R, E484Q, D614G, P681R, Q1071H | India, Oct-2020 |
| 8 | Lambda | C.37 | G75V, T76I, RSYLTPGD246-253 N, L452Q, F490S, T859N | Peru, Dec 2020 |