Table 1.
SARS-CoV-2 reinfections cases in india and their clinical characteristics.
| S.No. | References | (Age/Sex) | Comorbidity | Clinical symptoms of first infection | Clinical symptoms of reinfection | Confirmed reinfection (PCR/Antibody) | Intervening period (Days) | Sequencing Data (Genetic Variants) |
|---|---|---|---|---|---|---|---|---|
| 1 | (193) | 52/M | None | Asymptomatic | low-grade fever and body ache | RT PCR | 73 | clade from the first episode = 19A clade from the second episode = 20A |
| 2 | (39) | 47/M | None | Asymptomatic (civil official) |
Mild (fever, cough, and malaise) | RT PCR | 39 | 15 and 17 genetic variants in the genomes from the two episodes, respectively, of which 14variants were common between the two episodes. 22882T > G (Spike: N440K) variant in the genomes isolated from both episodes of infection |
| 3 | Patient 1, (178) | 27/M | None | Sore throat, rhinitis (2 days) | Cough, fever, myalgia (1 week) | RT PCR | 65 | clade from the first episode = 20A clade from the second episode = 19A |
| 4 | Patient 2, (178) | 31/M | None | asymptomatic | Myalgia, malaise (2 days) | RT PCR | 64 | clade from the first episode = 20B clade from the second episode = 20B |
| 5 | Patient 3, (178) | 24/F | None | Sore throat, rhinitis, Myalgia (5 days) |
Sore throat, rhinitis, Myalgia, Cough, fever (3 weeks) | RT PCR | 54 | clade from the first episode = 19A clade from the second episode = 20B |
| 6 | Patient 4, (178) | 51/F | Controlled hypertension | Fever, myalgia, dry cough (1 week) | Fever, myalgia, dry cough, nausea, abdominal pain, breathlessness (6 weeks) | RT PCR | 136 | clade from the first episode = 19A clade from the second episode = 20B |
| 7 | Patient 1, (195) | 61/M | None | Asymptomatic | Weakness, cough (2 days) | RT PCR | 75 | 10 unique variations between the viral genomes of both episodes (no variation in spike protein) |
| 8 | Patient 2, (195) | 38/M | Steroid usage (TB meningitis) | Hospitalized with headache and fever (1 day) | Fever (5 days) | RT PCR | 18 | 3 unique variations between both episodes ( one synonymous mutation in spike protein) |
| 9 | Patient 1 (194) | 25/M | None | Asymptomatic (Health care worker) | Asymptomatic (Health care worker) |
RT PCR | 108 | 9 unique variant differences between first and second episode of infection. |
| 10 | Patient 2, (194) | 28/F | None | Asymptomatic (Health care worker) |
Asymptomatic (Health care worker) |
RT PCR | 111 | 10 unique variant differences between first and second episode of infection. Genetic variation 22882T > G (S:N440K) within the receptor binding domain found in reinfection. |
| 11 | Patient 1,(196) | 18/F | Had PTB 5yrs ago | Fever, Cough (5 days) |
High grade fever, cough, dyspnea (2 days) | RT PCR | 5 | Not sequenced |
| 12 | Patient 2, (196) | 78/M | Coronary Artery disease | Fever, Cough (5 days) |
Fever, Cough Dyspnea (1 day) | RT PCR | 43 | Not sequenced |
| 13 | Patient 3, (196) | 42/M | None | Fever, Cough Dyspnea (4 days) | High grade fever and worsened dyspnea | RT PCR | 4 | Not sequenced |
| 14 | Patient 4, (196) | 25/F | None | Asymptomatic | Fever, Cough (2 days) |
RT PCR | 6 | Not sequenced |
| 15 | Patient 5, (196) | 64/M | None | Fever, Cough (2 days) |
Fever, Cough Dyspnea (3 days) | RT PCR | 17 | Not sequenced |
Abbreviations: M, Male; F, Female; RT, Real-time (RT-PCR).