Table 2.
Simple and multiple linear regression of determinants of eGFR
| Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|
| Beta (95%CI) | P value | Beta (95%CI) | P value | |
| Age, years | −0.87 (−0.91~−0.84) | <0.001 | −0.90 (−0.94~−0.86) | <0.001 |
| Sex (Male) | 12.06 (8.53~15.58) | <0.001 | 5.07 (2.06~8.08) | 0.001 |
| Duration of gout, years | −0.54 (−0.66~−0.43) | <0.001 | 0.08 (−0.03~0.18) | 0.16 |
| tophus | −4.63 (−6.35~−2.91) | <0.001 | −1.03 (−2.48~0.42) | 0.17 |
| BMI, kg/m2 | 0.30 (0.11~0.49) | 0.002 | 0.07 (−0.09~0.23) | 0.37 |
| SBP, mmHg | −0.20 (−0.24~-0.16) | <0.001 | 0.04 (−0.01~0.08) | 0.10 |
| DBP, mmHg | −0.25 (−0.31~-0.19) | <0.001 | −0.09 (−0.15~-0.03) | 0.008 |
| FBG, mmol/L | −2.78 (−3.47~−2.10) | <0.001 | 0.44 (−0.17~1.05) | 0.16 |
| TG, mmol/L | 0.04 (−0.32~0.41) | 0.81 | - | |
| TC, mmol/L | −2.16 (−2.86~−1.46) | <0.001 | −0.07 (−0.64~0.50) | 0.81 |
| SU, μmol/L | −0.02 (−0.02~−0.01) | <0.001 | −0.05 (−0.05~−0.04) | <0.001 |
| Urine pH | 2.80 (1.77~3.84) | <0.001 | 1.21 (0.38~2.04) | 0.004 |
| Hypertension | −13.23 (−14.74~−11.71) | <0.001 | −2.32 (−3.68~−0.96) | 0.001 |
| Diabetes | −12.51 (−15.77~−9.25) | <0.001 | −2.85 (−5.74~0.04) | 0.05 |
BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure; 1 mmHg=0.133kPa, FBG fasting blood glucose, TG triglycerides, TC total cholesterol, eGFR estimate glomerular filtration rate, SU serum urate