Table 4.
Add. mean pulmonary arterial pressure after diuretic change (as treated population stratified by sacubitril/valsartan)
| Average daily change of PAP mean (within 30 days of medication change) | Down‐titrated | Up‐titrated | P‐value a | ||
|---|---|---|---|---|---|
| Sacubitril/valsartan | Sacubitril/valsartan | ||||
| Yes (N = 11) | No (N = 35) | Yes (N = 34) | No (N = 69) | ||
| Decrease | 9 (81.82%) | 26 (74.29%) | 22 (64.71%) | 41 (59.42%) | 0.82 |
| Increase | 2 (18.18%) | 9 (25.71%) | 12 (35.29%) | 28 (40.58%) | |
PAP, pulmonary artery pressure.
a
Breslow–Day's test for homogeneity of the odds ratios.