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. 2021 Nov 16;9(1):11–20. doi: 10.1002/ehf2.13701

Table 5.

Specific thrombotic and bleeding risks according to the type of amyloidosis

Type of amyloidosis Prothrombotic risk factors Bleeding risk factors
AL

  • Nephrotic syndrome

  • Use of IMID

  • Heart failure

  • Higher free light chains and beta‐2 microglobulin level

  • Atrial fibrillation

  • Digestive involvement

  • Liver involvement

  • FX deficiency

  • Drug interactions (chemotherapy and oral anticoagulants)
TTR

  • Atrial fibrillation

  • Heart failure

  • Atrial myopathy

  • Age

  • Risk of fall (dysautonomia, conductive disorder)

  • Renal failure, haemodialysis

AL, immunoglobulin light chain amyloidosis; IMID, immunomodulatory drugs; TTR: transthyretin.