Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Nov 29;9(1):251–262. doi: 10.1002/ehf2.13693

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of European Society of Cardiology.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

PMC Copyright notice

(A) Representative planar (top) and single‐photon emission computed tomography/computed tomography (SPECT/CT; bottom) images of patients with Grade 1 myocardial tracer uptake and negative monoclonal protein test. White and red arrows indicate cardiac blood pools and positive cardiac uptake, respectively. (B) Flow chart of transthyretin amyloid cardiomyopathy (ATTR‐CM) diagnosis in patients with planar ^99mTc‐PYP scintigraphy Grade 1 and a negative monoclonal protein detection test. Endomyocardial, abdominal fat pad, or upper gastrointestinal tract biopsy is recommended. For patients who test negative with a biopsy, it is advisable to schedule regular follow‐up with scintigraphy after 6 months–1 year. Grade 1 in ^99mTc‐PYP scintigraphy refers to mild uptake less than rib uptake.