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. 2021 Dec 21;9(1):293–302. doi: 10.1002/ehf2.13761

TABLE 6.

Concordance statistics to evaluate predictive value of VE/VCO2 slope, peak VO2, and the combination of VE/VCO2 slope and peak VO2 in assessing risk of death + HF hospitalization across HF LVEF categories

C‐statistic
VE/VCO2 slope 95% CI Peak VO2 95% CI VE/VCO2 slope + peak VO2 95% CI
HFrEF 0.67 (0.63, 0.71) 0.71 (0.67, 0.75) 0.73 (0.69, 0.77)
HFmrEF 0.72 (0.60, 0.84) 0.85 (0.78, 0.92) 0.86 (0.80, 0.92)
HFpEF 0.71 (0.64, 0.78) 0.79 (0.74, 0.84) 0.80 (0.75, 0.85)

CI, confidence interval; HF, heart failure; HFmrEF, HF with mid‐range ejection fraction; HFpEF, HF with preserved ejection; HFrEF, HF with reduced ejection fraction; HR, hazard ratio; peak VO2, peak oxygen consumption; VE/VCO2, minute ventilation to carbon dioxide production ratio.