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. 2021 Dec 4;9(1):353–362. doi: 10.1002/ehf2.13743

Table 2.

Univariable and multivariable analysis: the likelihood (displayed as odds ratio [95% confidence interval]) of receiving guideline‐recommended therapy for diabetics compared with non‐diabetics

Univariable Multivariable
Model 1 Model 2 Model 3
Beta‐blocker 1.060 [0.932–1.205] 1.065 [0.998–1.138] 1.082 [0.950–1.231] 1.042 [0.914–1.188]
RAS inhibitor 0.804 [0.708–0.912] 0.803 [0.752–0.857] 0.848 [0.744–0.966] 0.853 [0.747–0.975]
MRA 1.007 [0.910–1.114] 1.011 [0.960–1.065] 0.965 [0.871–1.070] 0.952 [0.857–1.058]
Diuretics 1.564 [1.355–1.806] 1.526 [1.417–1.643] 1.393 [1.202–1.616] 1.284 [1.103–1.495]

COPD, chronic obstructive pulmonary disease; eGFR, estimated glomerular filtration rate; LVEF, left ventricular ejection fraction; MRA, mineralocorticoid receptor antagonist; NYHA, New York Heart Association; OSAS, obstructive sleep apnoea syndrome; RAS, renin–angiotensin system.

Model 1 included age and gender. Model 2 included age, gender, NYHA classification, and LVEF. Model 3 included age, gender, NYHA classification, LVEF, hypertension, COPD, OSAS, thyroid disease, renal insufficiency (defined as eGFR < 60 mL/min or a history of renal insufficiency), and atrial fibrillation.