Skip to main content
. Author manuscript; available in PMC: 2022 Jan 25.
Published in final edited form as: J Med Chem. 2017 Jan 5;60(2):641–657. doi: 10.1021/acs.jmedchem.6b01474

Figure 7.

Figure 7.

GOLD-based docking and scoring study of NSGMs binding to human plasmin. (A) Overlay of the best docked pose for NSGMs 1j (cyan), 2 (magenta), 3 (yellow), 4 (pink), 8 (white), 10 (blue), and 11 (green). (B) Relationship between −log IC50 (in M units) and GOLDSCORE. (C─F) Hydrogen bond interactions by inhibitors 1j, 2, 4, and 8 are shown. The key interacting residues are shown as spheres, and the inhibitors are shown as sticks.