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. 2022 Jan 11;7(1):35–48. doi: 10.1530/EOR-21-0083

Table 2.

Clinical manifestations and symptoms of Gorham–Stout disease.

Orthopedic - Pain
- Swelling
- Pathologic fractures
- Absence of bone/soft tissue consistency
- Bone deformities, kyphosis
Neurologic - Paraplegia
- Cerebrospinal fluid leakage (rhinorrhea, otorrhea, headache, migraine, nausea, vomiting)
- Hearing problems
Temporo-mandibular joint - Tinnitus
- Egophony
- Loose teeth
- Facial deformity
Thorax - Pleural or pericardial effusion
- Mediastinal mass
- Chylothorax
- Dyspnea
- Respiratory failure
Cutaneous - Lymphangiogenic malformations