Fig. 1.

Diversity of penguin TLRs. (A) Schematic diagram of the regions in TLR1A/1B and TLR2A/2B which have undergone gene conversion in birds. Yellow boxes indicate regions of gene conversion. Abbreviations: ECD, extracellular domain; TMD, transmembrane domain; TIR, Toll/interleukin-1 receptor domain. (B) Number of polymorphisms per TLR (excluding pseudogenes), stratified according to domain and polymorphism type. Apparent polymorphisms in gene-converted regions of the TLR1/2 family are shown in hatched boxes as sequence differences between orthologs cannot be distinguished from differences between the gene-converted paralogs in genomes generated using exclusively short-read technology.