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. 2021 Feb 10;59(2):122–132. doi: 10.1136/jmedgenet-2020-107501

Table 1.

Participant characteristics

ID Study arm Age (years) Ethnicity Marital status Parity Carrier status Personal history of BC RRM Number of relatives with OC Number of relatives with BC Ascertainment Postcode
ID-01 No surgery 40 Caucasian Single 0 BRCA1 No Yes 0 1 SDR High-risk FCC London
ID-02 RRSO 41 Caucasian Married 0 BRCA2 No Yes 0 1 FDR, 1 SDR High-risk FCC Essex
ID-03 RRESDO 37 Caucasian Married 3 BRCA2 No No 1 SDR 1 FDR, 1 SDR High-risk FCC Essex
ID-04 RRSO 46 Caucasian Married 0 BRCA1 No No 0 0 High-risk FCC London
ID-05 RRESDO 43 Caucasian Single 2 BRCA1 No No 1 SDR 3 SDR High-risk FCC London
ID-06 RRESDO 38 Caucasian Married 2 BRCA1 No Yes 0 3 SDR High-risk FCC Sussex
ID-07 No-surgery 36 Asian Single 1 BRCA1 No No 1 SDR 3 SDR High-risk FCC London
ID-08 RRESDO 46 Caucasian Married 3 BRCA2 No Yes 0 1 FDR, 1 SDR High-risk FCC Cambridge
ID-09 RRESDO 39 Caucasian Married 2 BRCA1 No Yes 1 FDR, 1 SDR 1 FDR High-risk FCC London
ID-10 No-surgery 39 Caucasian Married 0 BRCA1 No No 1 SDR 1 FDR High-risk FCC London
ID-11 RRESDO 35 Caucasian Married 2 BRCA2 No No 1 FDR 0 High-risk FCC Hertfordshire
ID-12 No-surgery 36 Caucasian Married 1 BRCA1 No No 2 SDR 1 SDR High-risk FCC London
ID-13 RRSO 45 Caucasian Married 1 BRCA2 No Yes 0 0 General gynaecology clinic Durham
ID-14 No-surgery 38 Caucasian Married 1 BRCA1 Yes* No† 0 0 High-risk FCC London
ID-15 RRESDO 38 Caucasian Married 2 BRCA2 No No 0 0 High-risk FCC Hertfordshire
ID-16 RRESDO 44 Caucasian Married 2 BRCA2 No No 2 SDR 1 SDR High-risk FCC Hampshire
ID-17 RRESDO 39 Caucasian Married 2 BRCA1 Yes‡ No† 0 0 GO clinic Newport
ID-18 RRESDO 44 Caucasian Single 2 BRCA2 No Yes 0 1 FDR, 2 SDR High-risk FCC London
ID-19 No surgery 34 Caucasian Married 2 BRCA1 No No 0 1 SDR Genetics clinic Surrey
ID-20 RRSO 46 Asian Married 2 BRCA1 No No 1 FDR, 2 SDR 2 SDR GO clinic Aberdeen
ID-21 RRESDO 44 Caucasian Married 2 BRCA2 Yes* Yes§ 1 FDR 1 FDR, 1 SDR GO clinic Devon
ID-22 RRSO 39 Caucasian Married 2 BRCA2 No No 0 1 FDR GO clinic Liverpool
ID-23 RRSO 40 Caucasian Single 2 BRCA1 No No 1 FDR, 1SDR 0 High-risk FCC Surrey
ID-24 RRSO 40 Caucasian Married 1 BRCA1 Yes‡ Yes*§ 0 2 FDR General gynaecology clinic Cleveland

*Oestrogen receptor positive breast cancer.

†Bilateral therapeutic mastectomies.

‡Triple negative breast cancer.

§Unilateral therapeutic mastectomy followed by contralateral risk reducing mastectomy.

BC, breast cancer; FCC, familial cancer clinic; FDR, first degree relative; GO, gynaecological oncology; OC, ovarian cancer; RRESDO, risk-reducing early salpingectomy with delayed oophorectomy; RRM, risk-reducing mastectomy; RRSO, risk-reducing salpingo-oophorectomy; SDR, second degree relative.